About
- Specialist HIV company established by GlaxoSmithKline (85%) and Pfizer (15%).
- Corporate members of the Council on Foreign Relations.
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Business
Portfolio
- 11 marketed products
- Protease inhibitors: Agenerase, Lexiva/Telzir, Viracept (N. America only).
- Nucleoside reverse transcriptase inhibitors: Combivir, Epivir/3TC, Epzicom/Kivexa, Retrovir/AZT, Trizivir, Ziagen.
- Non-nucleoside reverse transcriptase inhibitors: Rescriptor (US only).
- CCR5 antagonist: Selzentry/Celsentri.
2009
- £10 million for a partnership with other private and public sector bodies to address both the R&D and access challenges associated with HIV in Sub-Saharan Africa.
- Voluntary licence agreed, on a non-exclusive basis, with South Africa based Aspen Pharmacare Ltd for the manufacture of Abacavir.
- Shionogi-GlaxoSmithKline Pharmaceuticals LLC, in collaboration with the European AIDS Treatment Group and the Drug Development Committee of the AIDS Treatment Activists Coalition, to revise inclusion criteria for Study ING112276, a dose-ranging study of the investigational integrase inhibitor S/GSK1349572 in antiretroviral therapy-naïve patients.
- FDA approves expanded use of Selzentry (maraviroc) tablets, in combination with other antiretroviral agents, to include adult patients with CCR5-tropic HIV-1 virus who are starting treatment for the first time (treatment-naïve).
- Master Licence agreement with Shire Pharmaceuticals Group plc for products containing lamivudine.
- Shionogi & Company, co-developer of the integrase inhibitor.
2010
- $2 million/2 year partnership with Elizabeth Glaser Pediatric AIDS Foundation, primarily focus on Lesotho, Malawi and Swaziland. Support advocacy efforts to address policy barriers and support the prioritization of pediatric HIV care and treatment policies in other Foundation-supported countries, including Côte d'Ivoire, Kenya, Mozambique, Rwanda, South Africa, Tanzania, Uganda and Zambia.
- $2 million/2 year partnership with TREAT Asia, Bangkok-based program of amfAR (The Foundation for AIDS Research) to generate clinical evidence and develop strategies to support life-long pediatric care and help inform global treatment guidelines.
- Positive Action U.S. Southern Initiative selected organizations: Aid to Inmate Moms (Montgomery), Atlanta Harm Reduction Coalition, Family Service of Greater Baton Rouge, Grace House (Jackson), Positive Impact (Atlanta), Southwest Louisiana AIDS Council, Union Mission's J.C. Lewis Primary Health Care Center (Savannah); Focused on African American and Latinos in Alabama, Georgia, Louisiana, and Mississippi.
- The Not for Profit Price commitment for ARV portfolio to government and international procurement agencies, such as the Global Fund for AIDS, Tuberculosis and Malaria and UNICEF, expands to 69 countries where 80% of all people with HIV live.
2011
- One year trial pilot with the Welvista HIV treatment access program, developed by the Heinz Family Philanthropies in response to a call for help from the National Alliance of State and Territorial AIDS Directors to find ways to assist patients on AIDS Drug Assistance Program waiting lists and make enrollment simple for patients.
Positive Action for Children Fund
About
- First announced in July 2009.
- Builds upon the foundation of the long-standing Positive Action programme, established in 1992.
- Focuses on grants that pursue the 4 elements of the World Health Organization's strategic vision and comprehensive approach for addressing the mother-to-child transmission of HIV.
- 10 year programme to invest £50 million to support programmes focused on preventing HIV transmission from mother-to-child, as well as the health and well being of women, orphans and vulnerable children around the globe (at least 80% on sub-Saharan Africa).
2010 Projects
- £3.6 million.
- Ntankah Village Women Common Initiative Group (Republic of Cameroon).
- Public Health Research Institute of India.
- Partners in Health (Lesotho).
- Women Friendly Initiative (Nigeria).
- International Medical Foundation and the National Community of Women Living with HIV/AIDS (Uganda).
- Wakiso Integrated Rural Development Association (Uganda).
- Miroi Growers Cooperative Society (Uganda).
- Hodi (Zambia).
- Rajasthan Network for People Living with HIV/AIDS (India).
- Save the Children (Democratic Republic of Congo).
- Kenya AIDS Intervention Prevention Project Group.
- International Planned Parenthood Federation and Family Health Options Kenya.
Advisory Board
- Catherine Peckham, Board Chair: Professor of Paediatric Medicine at Institute of Child Health (UK).
- Ayorinde Ajayi: Regional Vice President at Pathfinder Inc.; Board member for the African Health and Population Research Center, which helped found (established in 1995 as a Population Policy Research Fellowship program of the Population Council, with funding from the Rockefeller Foundation); Chairman of the advisory committee on access for the International Partnership for Microbicides; Regional Director for sub-Saharan Africa managing Burkina Faso, Ghana, Kenya, Mali, Senegal, South Africa, and Zambia offices for Population Council; Regional vice president for the Pathfinder Fund; Consultant and Government Health Officer at Boston University; Government health officer in Nigeria; Consultant to the US Agency for International Development, the World Health Organization, and several United Nations agencies; Medical training at the University of Ibadan (Nigeria) and master's in public health from Boston University.
- Florence Manguyu: Consultant pediatrician in clinical practice at Aga Khan University Hospital; International AIDS Vaccine Initiative Advisor (Kenya); Member and past president of the Medical Women's International Association; Served on the International NGO Steering Committee for the 1994 International Conference on Population and Development and chaired the NGO Forum of the conference.
- Alejandra Trossero: Senior HIV Officer at International Planned Parenthood Federation (Malaysia).
- Winnie Ssanyu-Sseruma: HIV Coordinator at Christian AID (UK).
- Frika Chia Iskandar: Independent Consultant on HIV/AIDS; Member of the International Treatment Preparedness Coalition, TREATAsia and other networks nationally in Indonesia and internationally; Board member of the Global Network of People Living with HIV/AIDS (2003-2005); Co-Chair and coordinator of Women's Asia Pacific Network of People Living with HIV/AIDS (2002-2005); Founder of PITA Foundation (Jakarta).
Board of Directors
Julian Heslop
- Chairman.
- Chief Financial Officer for GSK since April 2005.
- Senior Vice President Operations Controller, member of the pharmaceutical operating committee and chaired the capital review team at GSK (2001-2005).
- Financial Controller of Glaxo Wellcome (1998-2001).
- Senior roles in brewing, property and food businesses and latterly Group Controller at Grand Metropolitan (1986).
- Management accounting and strategic planning roles at Imperial Brewing and Leisure (1979).
- Auditor at Stoy Hayward (1978).
- Chartered accountant working for John M. Winter (1977).
Dominique Limet
- Executive Team and CEO.
- Senior Vice President and Head of Personalised Medicine Strategy for GSK since April 2008.
- Member of GSK's Positive Action Steering Committee and board member of the GSK France Foundation, which supported a range of HIV/AIDS-related programmes around the world.
- Senior Vice President and Area Director for GSK's pharmaceutical business in Southern & Eastern Europe (2003-2008).
- General Manager of GSK France (2000-2003).
- Marketing and Sales Director (1996), General Manager Operations (1999) and Chairman and Managing Director (2000) at Glaxo Wellcome in France.
- Marketing and management positions at Ciba-Geigy (1985-1996).
- Medicomarketing advisor at Negma Laboratory (1983-1985).
- Doctorate in Medicine, specialization in occupational medicine; Marketing and Management qualifications at Insead.
Cees Heiman
- Regional President of Europe (including Australia/New Zealand on an interim basis) for the Specialty Care Business Unit at Pfizer.
- Regional President of Pfizer Central and Eastern Europe since December 2007 and Country Manager for Italy since May 2008.
- Country Manager of Poland, followed by Country Manager of Belgium/Luxembourg (2000-2004).
- Vice President of Marketing and New Product Development for Pfizer Japan.
- Country Manager of Hungary (1995).
- Assignments in the Marketing and New Product departments, first in the Netherlands and subsequently in New York Headquarters (launch of Norvasc) and in India.
- Medical Department of Pfizer Netherlands (1982).
- Bachelor's and master's degrees in Pharmacy from Leiden University in the Netherlands and licensed pharmacist.
Zhi Hong
- Senior Vice President and Head of the Infectious Diseases Centre of Excellence for Drug Discovery at GSK since 2007.
- Executive Vice President and Chief Scientific Officer of Ardea Biosciences Inc.
- Vice President and Head of Research at Valeant Pharmaceuticals International.
- Research and management roles at Schering-Plough Research Institute.
- Bachelor's degree in Biochemistry from Fudan University in Shanghai and Ph.D. in Biochemistry from the State University of New York at Buffalo.
Abbas Hussain
- President Emerging Markets of GSK since June 2009.
- Non-executive director of Aspen Pharmacare Holdings Limited.
- Sales Representative GP & Hospital Sales East London (1988); Associate of Market Research & New Product Planning and subsequently District Sales Manager in Austrlia (1990); Associate of Global Product Planning (Cardiovascular Business Unit) in Indianapolis (1994); Associate of Business Development Asia Pacific (1995); Pharmaceutical Sales & Marketing Director in India (1996); Managing Director of Turkey (1998); General Manager Lilly Deutschland and General Manager and Speaker Lilly Pharma Holding GmbH (2001); European Mid-Size Area Director (2003); Vice President of Europe with specific responsibility for the Western European Mid-Size countries, Africa & Middle East Area/Commonwealth of Independent States and Central & Eastern Europe regions; and President Europe for Eli Lilly and Company.
- Degree in Medicinal Chemistry & Pharmacology from Loughborough University of Technology, UK.
Duncan Learmouth
- Senior Vice President, Corporate Communications and Community Partnerships, and member of the Corporate Executive Team of GSK since July 2006.
- Vice President, Global Investor Relations and Competitive Excellence of GSK.
- Joined Glaxo Wellcome in 1991; Investor Relations department (1997); Vice President of Investor Relations (2000); Vice President, Global Investor Relations with responsibility for the global IR function (2001).
- Financial Investigations and Trading Arrangements departments, and Financial Controller of Adechsa S.A., based in Zug, Switzerland.
- Chartered Accountant (1991) at Deloitte and Touche (1988) in London.
- Degree in Chemistry at Durham University.
Martin Mackay
- President of Pfizer Global Research & Development since 2007.
- Director of Discovery Biology in the UK (1995); Senior Director, Head of Biology (1997); Vice President UK Discovery (1998); Senior Vice President, Head of Worldwide Discovery (1999); Senior Vice President, Head of Worldwide Research and Technology (2003); and Vice President PGRD, Head of Worldwide Development (2007) at Pfizer.
- Advanced Drug Delivery Research Unit and Head of Drug Preformulation and Delivery in Sussex, UK; Head of Molecular and Cell Biology, CNS Research, in Basel, Switzerland (1993-1995) at Ciba-Geigy.
- Postdoctoral research fellowship working on malarial vaccines with Professor John Scaife at the University of Edinburgh and Professor Uli Certa at Hoffman La-Roche Pharmaceuticals in Basel, Switzerland.
- In Antibacterial Discovery at Beecham Pharmaceuticals in Surrey, UK.
- Microbiology First Class Honors Degree at Heriot-Watt University and PhD in Molecular Genetics at the University of Edinburgh.
Ian McCubbin
- Senior Vice President of Strategy, Logistics and External Supply at GSK; joined in 1985, senior production, logistics and continuous improvement roles including Site Director at the Ware manufacturing site in the UK.
- Senior operational roles in both Merck Generics and IVAX.
- Degree in Pharmacy from Heriott Watt University, Edinburgh.
Ellen Strahlman
- Senior Vice President and Chief Medical Officer for GSK since August 2008.
- Vice President and Worldwide Therapeutic Area Head for Ophthalmology (2005) and Vice President, Worldwide Business Development at Pfizer.
- Global Vice President of Development for the Ophthalmics Business Unit at Novartis Pharmaceuticals.
- Chief Executive of Virgoen Ltd, a small biotech company in the UK specialising in anti-viral drug discovery and development.
- Senior roles at Bausch & Lomb and Merck & Co.
- Masters Degree in Health Sciences, Epidemiology & Statistics, from the Johns Hopkins Bloomberg School of Public Health as a Carnegie-Mellon Fellow.
- Graduate of Harvard University, Biochemical Sciences and Applied Mathematics, and medical degree from the Johns Hopkins School of Medicine.
Executive Team
Bill Collier
- Head of the North America region, responsible for the businesses in the US, Canada and Puerto Rico.
- At GSK: Sales and Marketing positions in the UK and in Global Commercial Development; Area Director for Sub Saharan Africa operations (included marketing and sales responsibility for the HIV product portfolio); Senior VP Sales for US Pharmaceuticals; Office of the CEO coordinating the Support Function Review and supporting launch excellence in GSK Japan.
- BSc Hons in Mathematics and Management Sciences from Manchester University (UK).
Terry Crandall
- Head Legal Counsel and Company Secretary.
- Member of the North Carolina Bar and the Illinois Bar.
- Assistant General Counsel, Sales, Marketing & Managed Care, US Legal Operations, responsible for providing support to HIV products Epzicom, Combivir and Trizivir, as well as the HIV sales force at GSK.
- BA degrees with Honours in English and Psychology from Bucknell University, Phi Beta Kappa, and Law degree from the University of North Carolina, Chapel Hill.
Saskia Fontein
- Head of Commercial Strategy, including global product strategy for new and marketed products and commercial portfolio management.
- Market Analytics in New Product Development covering HIV and other viral diseases (2001); Worldwide Marketing and leadership role in developing global HIV portfolio, launching Celsentri (marketed in the US as Selzentry) and leading the HIV disease area strategy (2003); HIV prevention strategy at Pfizer.
Manuel Goncalves
- Head of Government Affairs, Patient Advocacy, Community Partnership and Access.
- At GSK: Medical & Regulatory Affairs Director Portugal (1984); series of commercial roles of increasing seniority in France, the UK and Portugal; Vice President and General Manager of pharmaceuticals business in Portugal (1997); significant experience in working with members of the government and local community on market access, healthcare policy and industry reputation issues while running the commercial business including the HIV product portfolio.
- Elected member of the Portuguese Medical Academy and the General Council of Lisbon Public University (Nova).
Mary Kerr
- Head of Europe, responsible for business.
- At GSK: Field-based roles (1989-1992); product management (1992-1995); Business Unit Head, Neurosciences and Antibiotics in the UK (1995-1997); Director European Market Development (Cardiovascular, Respiratory, and Metabolic & Oncology) and then Group Director and Head of European Market Development (1997-1999); Group Director and Head of the Global Product Strategy Neurosciences and Gastrointestinal team (1999); VP Pharmacogenetics and Diagnostics in R&D; Marketing Director; European Critical Diseases Business Unit (2004-2009) that evolved from an idea into a flourishing European business.
- BTG-funded Post-Doctoral Fellow at the Michigan Cancer Foundation in Detroit.
- BSc and PhD in Pharmacology from the University of Bradford and MBA from the University of Kingston.
John Pottage
- Chief Scientific and Medical Officer, oversees R&D, Regulatory, Safety and Medical Affairs.
- Former Senior Vice president Infectious Diseases Medicine Development Centre for GSK.
- Senior positions at Vertex Pharmaceuticals and Achillion Pharmaceuticals.
- Associate Professor of Internal Medicine in the Section of Infectious Diseases at Rush Medical College in Chicago, and Director of the Outpatient HIV Centre.
David Pritchard
- Head of the International region, responsible for the business outside North America and Europe.
- At GSK: Senior roles in sales and marketing positions (1988); General Manager Ukraine (2002); Area General Manager Developing Markets Eurasia (2004-2008), responsible for nine Caucasus and Central Asian markets; VP and General Manager for South Africa business.
- BSc Hons in Biochemistry and Microbiology from Leeds University.
Kris Webb
- Head of Human resources.
- Human resources Director for GSK in Australia.
- Human resources director roles in the commercial law firm Clayton Utz, PriceWaterhouseCoopers and BP Australia.
- Bachelor of Business degree in Human resources and Industrial Relations from the Royal Melbourne Institute of Technology.
Subesh Williams
- Chief Financial Officer, oversees Finance and Business Development.
- Roles within finance (1994); Vice president Corporate Development at GSK.